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ea0073oc12.4 | Oral Communications 12: Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Improvements in long-term appetite-regulating hormones in response to a combined lifestyle intervention for obesity

Kuckuck Susanne , van der Valk Eline S. , Scheurink Anton J. W. , van den Berg Sjoerd A. A. , van Rossum Elisabeth F. C.

IntroductionAltered levels of hormonal appetite regulators have been observed in obesity (BMI ≥ 30.0 kg/m2), most prominently increases of insulin and leptin (indicating resistance) as well as decreases of adiponectin–all of which are long-term energy regulators and adiposity signals. Disrupted signaling of these hormones may have detrimental effects on metabolism, but may also promote weight gain. Weight loss is often accompanied ...

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ea0073oc7.3 | Oral Communications 7: Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Long-term glucocorticoids are associated with increased odds of metabolic syndrome after an intensive combined lifestyle intervention

Mohseni Mostafa , Van der Valk Eline S. , Lengton Robin , Savas Mesut , Rijke Yolanda De , Van den Berg Sjoerd A.A. , Van der Voorn Bibian , Van Rossum Liesbeth F.C

BackgroundLong-term glucocorticoids, as measured in scalp hair (HairGC), are associated with obesity and the metabolic syndrome (MetS). It is not known whether this represents a state of obesity or whether chronic hypercortisolism may influence the course or reversibility of obesity. In this study we longitudinally examine the relation between HairGC concentrations and metabolic syndrome parameters in patients with obesity who participate in a 1.5 year i...

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Endocrine Abstracts

Improvements in long-term appetite-regulating hormones in response to a combined lifestyle intervention for obesity

Long-term glucocorticoids are associated with increased odds of metabolic syndrome after an intensive combined lifestyle intervention

BiosciAbstracts